Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 1/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526209 | 0.92 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Water SCHEMBL9775975 | 0.91 | KDM4E (0.67) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8942177 | 0.89 | LMNA (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8941906 | 0.86 | LMNA (0.50) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8941879 | 0.86 | LMNA (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8942218 | 0.86 | ALDH1A1 (0.45) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8941976 | 0.86 | ALDH1A1 (0.45) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8942340 | 0.86 | DPP4 (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9775909 | 0.84 | KCNH2 (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8941960 | 0.84 | DPP4 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |