Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941879 | 0.92 | LMNA (0.61) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942177 | 0.89 | LMNA (0.47) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942154 | 0.86 | KDM4E (0.58) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942218 | 0.85 | ALDH1A1 (0.45) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8941976 | 0.85 | ALDH1A1 (0.45) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942137 | 0.84 | LMNA (0.49) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8942224 | 0.83 | ALDH1A1 (0.48) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9775969 | 0.82 | ALDH1A1 (0.67) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8941921 | 0.82 | ALDH1A1 (0.46) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9529605 | 0.82 | LMNA (0.71) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |