Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942657 | 0.91 | ALOX5 (0.56) | KDM4EALDH1A1ALOX5SMN1; SMN2L3MBTL1 | |
| SCHEMBL8942625 | 0.84 | ALOX5 (0.47) | ALDH1A1ALOX5SMN1; SMN2TDP1MEN1 | |
| SCHEMBL8782626 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1ALOX5SMN1; SMN2HTR1D | |
| SCHEMBL8942608 | 0.83 | FDFT1 (0.48) | ALOX5FDFT1 | |
| SCHEMBL8942663 | 0.79 | ALOX5 (0.46) | KDM4EALDH1A1ALOX5SMN1; SMN2HTR1D | |
| SCHEMBL8942388 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1ALOX5SMN1; SMN2HTR1D | |
| SCHEMBL8942484 | 0.76 | PARP10 (0.50) | ALDH1A1ALOX5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8782786 | 0.74 | CYP1A2 (0.61) | KDM4EALDH1A1ALOX5SMN1; SMN2MEN1 | |
| SCHEMBL8783294 | 0.73 | MEN1 (0.57) | ALDH1A1ALOX5SMN1; SMN2LMNAMEN1 | |
| SCHEMBL8942402 | 0.73 | EPOR (0.46) | ALOX5LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |