Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942794 | 0.82 | ALOX5 (0.53) | KDM4EALDH1A1HTR1DHTR1BALOX5 | |
| SCHEMBL8942292 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1HTR1DHTR1BALOX5 | |
| SCHEMBL8783449 | 0.76 | ALOX5 (0.57) | ALDH1A1ALOX5LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8783528 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HTR1DHTR1BALOX5 | |
| SCHEMBL8783536 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HTR1DHTR1BALOX5 | |
| SCHEMBL8942663 | 0.70 | ALOX5 (0.46) | KDM4EALDH1A1HTR1DHTR1BALOX5 | |
| SCHEMBL8942657 | 0.69 | ALOX5 (0.56) | KDM4EALDH1A1ALOX5RAB9ASMN1; SMN2 | |
| SCHEMBL8782626 | 0.69 | KDM4E (0.61) | KDM4EALDH1A1HTR1DHTR1BALOX5 | |
| SCHEMBL8942773 | 0.69 | ALOX5 (0.61) | ALDH1A1HTR1DHTR1BALOX5LMNA | |
| SCHEMBL8782313 | 0.69 | LMNA (0.69) | KDM4EALDH1A1HTR1DHTR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |