Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942623 | 0.85 | HPGD (0.46) | ALOX5SMN1; SMN2ERCC5FEN1HPGD | |
| SCHEMBL8942653 | 0.83 | CA1 (0.47) | PARP10CA1CA2HPGDKMT2A | |
| SCHEMBL8942712 | 0.82 | PARP14 (0.45) | PARP10ERCC5FEN1MMP1MEN1 | |
| SCHEMBL8942429 | 0.82 | PARP10 (0.45) | PARP10HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL8942399 | 0.82 | CTNNB1 (0.52) | SMN1; SMN2HPGDMEN1KMT2AATM | |
| SCHEMBL8942657 | 0.82 | ALOX5 (0.56) | PARP10ALOX5SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL8783140 | 0.81 | CA12 (0.58) | PARP10ALOX5SMN1; SMN2MCHR1CA12 | |
| SCHEMBL8942402 | 0.80 | EPOR (0.46) | PARP10ALOX5ERCC5FEN1MEN1 | |
| SCHEMBL8942307 | 0.80 | KLKB1 (0.43) | ALOX5HPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL8942679 | 0.79 | MAPT (0.47) | PARP10ALOX5SMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |