Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942292 | 0.91 | KDM4E (0.54) | ALOX5SMN1; SMN2RAB9AGLAGAA | |
| SCHEMBL8942625 | 0.88 | ALOX5 (0.47) | ALOX5SMN1; SMN2GLAGAAHTT | |
| SCHEMBL8782786 | 0.82 | CYP1A2 (0.61) | ALOX5SMN1; SMN2RAB9AGLAGAA | |
| SCHEMBL8942484 | 0.82 | PARP10 (0.50) | ALOX5SMN1; SMN2RAB9AALDH1A1PARP10 | |
| SCHEMBL8942608 | 0.79 | FDFT1 (0.48) | ALOX5FFAR1 | |
| SCHEMBL8942399 | 0.74 | CTNNB1 (0.52) | SMN1; SMN2RAB9AGAAHTTKDM4E | |
| SCHEMBL8782626 | 0.74 | KDM4E (0.61) | ALOX5SMN1; SMN2RAB9AGLAGAA | |
| SCHEMBL8783140 | 0.74 | CA12 (0.58) | ALOX5SMN1; SMN2RAB9AHTTALDH1A1 | |
| SCHEMBL8942307 | 0.72 | KLKB1 (0.43) | ALOX5RAB9ALTA4HALDH1A1NPC1 | |
| SCHEMBL8942663 | 0.72 | ALOX5 (0.46) | ALOX5SMN1; SMN2RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |