Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847673 | 1.00 | DRD2 (0.41) | DRD2DRD4KDM4EOPRM1OPRK1 | |
| SCHEMBL6141223 | 0.95 | DRD2 (0.43) | DRD2DRD4KDM4EOPRM1OPRK1 | |
| SCHEMBL10233648 | 0.86 | DRD2 (0.44) | DRD2DRD4KDM4ECRHBPCRHR2 | |
| SCHEMBL8942319 | 0.84 | DRD2 (0.46) | DRD2DRD4KDM4ECRHBPCRHR2 | |
| SCHEMBL30887165 | 0.83 | DRD2 (0.46) | DRD2DRD4KDM4ECRHBPCRHR2 | |
| SCHEMBL11183111 | 0.83 | DRD2 (0.46) | DRD2DRD4KDM4ECRHBPCRHR2 | |
| SCHEMBL596045 | 0.83 | DRD2 (0.46) | DRD2DRD4KDM4ECRHBPCRHR2 | |
| SCHEMBL11420280 | 0.83 | CRHBP (0.42) | DRD2DRD4KDM4ECRHBPCRHR2 | |
| SCHEMBL10886763 | 0.81 | CRHBP (0.43) | DRD2DRD4KDM4ECRHBPCRHR2 | |
| SCHEMBL9777037 | 0.81 | DRD2 (0.42) | DRD2DRD4KDM4EOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434611-A2 | Azo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |