Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942633 | 0.96 | TP53 (0.52) | RAB9ANPC1GAATP53TSHR | |
| SCHEMBL8942653 | 0.84 | CA1 (0.47) | RAB9ANPC1KMT2A | |
| SCHEMBL8782667 | 0.82 | NPC1 (0.58) | RAB9AMEN1NPC1KMT2AMMP1 | |
| SCHEMBL8942404 | 0.80 | SAE1 (0.51) | MEN1KMT2A | |
| SCHEMBL8783244 | 0.79 | NPC1 (0.55) | RAB9AMEN1NPC1KMT2AMMP1 | |
| SCHEMBL8942484 | 0.79 | PARP10 (0.50) | RAB9AMEN1NPC1KMT2AMMP1 | |
| SCHEMBL8942382 | 0.76 | CYP2C9 (0.47) | MEN1NPC1KMT2ATSHR | |
| SCHEMBL28576237 | 0.74 | NPC1 (0.62) | RAB9AMEN1NPC1KMT2AMMP1 | |
| SCHEMBL8942623 | 0.74 | HPGD (0.46) | RAB9ANPC1GAA | |
| SCHEMBL8942624 | 0.73 | TLR4 (0.47) | RAB9AMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |