Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942623 | 0.82 | HPGD (0.46) | ALDH1A1KDM4EMAPTNPC1GSK3B | |
| SCHEMBL8942653 | 0.81 | CA1 (0.47) | CYP1A2KMT2AKDM4ENPC1 | |
| SCHEMBL8942712 | 0.80 | PARP14 (0.45) | MEN1KMT2A | |
| SCHEMBL8942817 | 0.79 | GAA (0.42) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8942484 | 0.79 | PARP10 (0.50) | MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8782677 | 0.78 | CYP1A2 (0.61) | CYP2C19CYP1A2TSHRNFKB1MAOB | |
| SCHEMBL8942432 | 0.76 | RAB9A (0.46) | TSHRMEN1KMT2ANPC1 | |
| SCHEMBL8942600 | 0.76 | KDM4E (0.46) | CYP2C9CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL8942383 | 0.76 | ALDH1A1 (0.45) | CYP2C9CYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL8942408 | 0.75 | TNKS (0.39) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |