Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942432 | 0.96 | RAB9A (0.46) | TP53TSHRTHRATHRBNPC1 | |
| SCHEMBL8783244 | 0.83 | NPC1 (0.55) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL8942653 | 0.81 | CA1 (0.47) | NPC1RAB9A | |
| SCHEMBL8782667 | 0.79 | NPC1 (0.58) | NPC1LMNAMAPTRAB9AHSD17B10 | |
| SCHEMBL28576237 | 0.79 | NPC1 (0.62) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL8942404 | 0.77 | SAE1 (0.51) | — | |
| SCHEMBL8942484 | 0.76 | PARP10 (0.50) | NPC1RAB9A | |
| SCHEMBL15172203 | 0.75 | TP53 (0.65) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL8108920 | 0.74 | TP53 (0.73) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL19723267 | 0.74 | TP53 (0.73) | TP53TSHRPLA2G4BRARBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |