Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942429 | 0.84 | PARP10 (0.45) | PARP10PARP1PARP2HPGDMTNR1A | |
| SCHEMBL8942753 | 0.84 | PARP1 (0.52) | PARP1NPC1RAB9AHPGDMTNR1A | |
| SCHEMBL8942432 | 0.84 | RAB9A (0.46) | NPC1RAB9AKMT2A | |
| SCHEMBL8942484 | 0.83 | PARP10 (0.50) | CA1CA2PARP10NPC1RAB9A | |
| SCHEMBL8942633 | 0.81 | TP53 (0.52) | NPC1RAB9A | |
| SCHEMBL8783847 | 0.80 | NPC1 (0.61) | CA1CA2NPC1RAB9AHPGD | |
| SCHEMBL8942623 | 0.78 | HPGD (0.46) | NPC1RAB9AKDM4EHPGDDRD2 | |
| SCHEMBL8942585 | 0.74 | MEN1 (0.42) | PARP10PARP1NPC1RAB9AKDM4E | |
| SCHEMBL31483087 | 0.72 | MTNR1A (0.73) | NPC1RAB9AMTNR1AMTNR1BDRD2 | |
| SCHEMBL7924560 | 0.72 | SMN1; SMN2 (0.73) | NPC1RAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |