Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942778 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTALOX5CYP2C9CYP2C19 | |
| SCHEMBL8942609 | 0.89 | ALOX5 (0.52) | ALDH1A1MAPTALOX5CYP2C9CYP2C19 | |
| SCHEMBL8942383 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTALOX5CYP2C9CYP2C19 | |
| SCHEMBL8783317 | 0.74 | ALOX5 (0.56) | ALDH1A1MAPTALOX5CYP2C9CYP2C19 | |
| SCHEMBL8783087 | 0.74 | ALOX5 (0.56) | ALDH1A1MAPTALOX5CYP2C9CYP2C19 | |
| SCHEMBL8783077 | 0.74 | ALOX5 (0.56) | ALDH1A1MAPTALOX5CYP2C9CYP2C19 | |
| SCHEMBL8942397 | 0.72 | ALOX5 (0.52) | ALOX5CARM1PRMT6ACACB | |
| SCHEMBL8782265 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX5NPY5RP2RX3 | |
| SCHEMBL8783375 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX5NPY5RP2RX3 | |
| SCHEMBL8782267 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX5NPY5RP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |