Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942311 | 0.88 | ALOX5 (0.49) | ALDH1A1MAPTLTA4HEPHX2ALOX5 | |
| SCHEMBL8942702 | 0.88 | EPHX2 (0.38) | ALDH1A1MAPTEPHX2ALOX5MAPK1 | |
| SCHEMBL8942307 | 0.88 | KLKB1 (0.43) | ALDH1A1MAPTLTA4HEPHX2ALOX5 | |
| SCHEMBL8783029 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTLTA4HEPHX2ALOX5 | |
| SCHEMBL8942778 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTCYP2C9CYP2C19P2RX3 | |
| SCHEMBL8942588 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTCYP2C9CYP2C19P2RX3 | |
| SCHEMBL8942712 | 0.76 | PARP14 (0.45) | LTA4HEPHX2P2RX3 | |
| SCHEMBL8942382 | 0.76 | CYP2C9 (0.47) | ALDH1A1MAPTCYP2C9CYP2C19KDM4E | |
| SCHEMBL8782994 | 0.74 | KLKB1 (0.48) | ALDH1A1MAPTALOX5NPSR1MAPK1 | |
| SCHEMBL8783508 | 0.74 | ALOX5 (0.54) | ALDH1A1MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |