Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782837 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1LMNAALOX5HTR1D | |
| SCHEMBL8782847 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1LMNAALOX5HTR1D | |
| SCHEMBL8782561 | 0.81 | ALOX5 (0.48) | SMN1; SMN2ALDH1A1LMNAALOX5HTR1D | |
| SCHEMBL8942794 | 0.77 | ALOX5 (0.53) | SMN1; SMN2ALDH1A1LMNAALOX5HTR1D | |
| SCHEMBL8783536 | 0.75 | KDM4E (0.57) | SMN1; SMN2ALDH1A1LMNAALOX5HTR1D | |
| SCHEMBL8783528 | 0.75 | KDM4E (0.57) | SMN1; SMN2ALDH1A1LMNAALOX5HTR1D | |
| SCHEMBL8942402 | 0.74 | EPOR (0.46) | LMNAALOX5AKR1C3ERCC5FEN1 | |
| SCHEMBL8942426 | 0.74 | PPARG (0.44) | ALDH1A1LMNAALOX5PTGESACACA | |
| SCHEMBL8782273 | 0.73 | ACACB (0.45) | PTGESACACA | |
| SCHEMBL9876838 | 0.72 | AKR1C3 (0.64) | SMN1; SMN2ALDH1A1LMNAALOX5AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |