Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782273 | 0.91 | ACACB (0.45) | PPARGPPARAPTGESACACBNPY5R | |
| SCHEMBL8942682 | 0.74 | SMN1; SMN2 (0.53) | PTGESALDH1A1ACACAALOX5LMNA | |
| SCHEMBL8783389 | 0.73 | LTA4H (0.46) | PPARGPPARAPTGESNPY5RFDFT1 | |
| SCHEMBL12440458 | 0.72 | P2RX3 (0.58) | PPARGPPARAFDFT1DAGLAALDH1A1 | |
| SCHEMBL9262220 | 0.72 | PPARG (0.56) | PPARGPPARAFDFT1DAGLAALDH1A1 | |
| SCHEMBL8782953 | 0.71 | ALOX5 (0.42) | PPARGPPARAALDH1A1P2RX3ALOX5 | |
| SCHEMBL1421946 | 0.71 | PPARG (0.61) | PPARGPPARADAGLAFAAHP2RX3 | |
| SCHEMBL8942608 | 0.70 | FDFT1 (0.48) | PTGESFDFT1ALOX5 | |
| SCHEMBL8942651 | 0.70 | PTGES (0.48) | PPARGPPARAPTGESACACBNPY5R | |
| SCHEMBL8783189 | 0.69 | DAGLA (0.47) | PPARGPPARAPTGESDAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |