SCHEMBL8943028

SCHEMBL8943028

C=CCc1ccc(OCc2ccc(O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.59
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
PTGS1 P23219 1/20 0.58
SLC6A2 P23975 1/20 0.58
CYP2C19 P33261 1/20 0.58
PTGS2 P35354 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HIF1A Q16665 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
ALDH1A1 P00352 3/20 0.53
TP53 P04637 2/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
F2 P00734 2/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737615 1.00 APP (0.59) APPLMNACYP1A2PTGS1SLC6A2
SCHEMBL30083980 0.85 LMNA (0.58) APPLMNACYP1A2PTGS1SLC6A2
Chavicol SCHEMBL30870 0.84 XDH (0.58) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL5633306 0.84 APP (0.79) APPLMNACYP1A2PTGS1SLC6A2
SCHEMBL11578826 0.84 APP (0.79) APPLMNACYP1A2PTGS1SLC6A2
SCHEMBL28610013 0.84 SMN1; SMN2 (0.52) APPALDH1A1TP53CYP3A4ALOX15
SCHEMBL9735745 0.84 ALDH1A1 (0.52) APPALDH1A1TP53CYP3A4ALOX15
SCHEMBL9736380 0.84 ALDH1A1 (0.52) APPALDH1A1TP53CYP3A4ALOX15
SCHEMBL9797652 0.84 SMN1; SMN2 (0.79) APPALDH1A1TP53CYP3A4ALOX15
Chavicol SCHEMBL10511637 0.82 XDH (0.56) CYP1A2PTGS1SLC6A2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
US-5149462-A Used as ferroelectric liquid crystal MITSUBISHI RAYON COMPANY LTD. (JP) 1992-09-22 US disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed
EP-0409066-A2 Optically active compound for liquid crystal and its use MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-01-23 EP disclosed