SCHEMBL9735745

SCHEMBL9735745

C=CCc1ccc(COc2ccc([O])cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
APP P05067 7/20 0.46
F2 P00734 2/20 0.43
PARP10 Q53GL7 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
TMPRSS6 Q8IU80 1/20 0.43
ST14 Q9Y5Y6 1/20 0.43
PTPRC P08575 1/20 0.42
PTPN2 P17706 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPRZ1 P23471 1/20 0.40
FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9736380 1.00 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL8943028 0.84 APP (0.59) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL30083980 0.84 LMNA (0.58) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL9737615 0.84 APP (0.59) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL4319803 0.82 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL9797652 0.82 SMN1; SMN2 (0.79) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL28610013 0.82 SMN1; SMN2 (0.52) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL10539027 0.80 NR4A2 (0.66) ALDH1A1SMN1; SMN2PARP10PTPRCPTPN2
SCHEMBL9327054 0.76 MAOB (0.67) ALDH1A1SMN1; SMN2APPMAOBBCHE
SCHEMBL5606537 0.76 MAOB (0.67) APPPARP10PTPN1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5149462-A Used as ferroelectric liquid crystal MITSUBISHI RAYON COMPANY LTD. (JP) 1992-09-22 US disclosed
EP-0409066-A2 Optically active compound for liquid crystal and its use MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-01-23 EP disclosed