SCHEMBL8943600

SCHEMBL8943600

Cc1ccc(Nc2ccc(OCCCOc3ccc(Nc4ccc(C)cc4)cc3Nc3ccc(C)cc3)c(Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.41
L3MBTL1 Q9Y468 8/20 0.40
GAA P10253 3/20 0.40
MEN1 O00255 1/20 0.40
G6PD P11413 1/20 0.40
KMT2A Q03164 1/20 0.40
EGFR P00533 1/20 0.39
L3MBTL4 Q8NA19 1/20 0.39
L3MBTL3 Q96JM7 1/20 0.39
MAPT P10636 9/20 0.39
TDP1 Q9NUW8 3/20 0.39
APP P05067 1/20 0.38
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
RAPGEF4 Q8WZA2 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GFER P55789 1/20 0.38
ATM Q13315 1/20 0.38
CYP1A2 P05177 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943646 0.97 L3MBTL4 (0.42) HPGDL3MBTL1GAAMEN1G6PD
SCHEMBL8943794 0.95 L3MBTL4 (0.41) HPGDL3MBTL1GAAMEN1G6PD
SCHEMBL8943812 0.95 L3MBTL4 (0.41) HPGDL3MBTL1GAAMEN1G6PD
SCHEMBL8944014 0.95 HPGD (0.42) HPGDL3MBTL1GAAMEN1G6PD
SCHEMBL8944086 0.86 MAPT (0.49) HPGDL3MBTL1GAAMEN1KMT2A
SCHEMBL8943884 0.84 HPGD (0.39) HPGDL3MBTL1GAAMEN1G6PD
SCHEMBL8944045 0.84 CTSV (0.43) HPGDL3MBTL1GAAMEN1KMT2A
SCHEMBL8943649 0.82 ALDH1A1 (0.41) HPGDL3MBTL1GAAMEN1KMT2A
SCHEMBL8943948 0.81 NPSR1 (0.51) MEN1KMT2AEGFRMAPTCYP1A2
SCHEMBL8944010 0.81 MAPT (0.53) HPGDL3MBTL1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed