SCHEMBL8944045

SCHEMBL8944045

Cc1ccc(Nc2ccc(OCc3ccc(COc4ccc(Nc5ccc(C)cc5)cc4Nc4ccc(C)cc4)cc3)c(Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 3/20 0.43
CTSL P07711 3/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
GAA P10253 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C19 P33261 3/20 0.41
MAPT P10636 2/20 0.41
RECQL P46063 2/20 0.41
LMNA P02545 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP19A1 P11511 1/20 0.40
MAOB P27338 2/20 0.40
CSF1R P07333 2/20 0.39
HDAC1 Q13547 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943784 0.90 EGFR (0.44) CTSVCTSLALDH1A1CYP1A2CYP2C19
SCHEMBL8944014 0.85 HPGD (0.42) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL8943968 0.85 CSF1R (0.54) CTSVCTSLNPC1RAB9AGAA
SCHEMBL8943646 0.84 L3MBTL4 (0.42) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL8943600 0.84 HPGD (0.41) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL8944340 0.83 CTSV (0.44) CTSVCTSLNPC1RAB9AGAA
SCHEMBL8943794 0.83 L3MBTL4 (0.41) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL8943812 0.83 L3MBTL4 (0.41) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL8943884 0.81 HPGD (0.39) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL8944086 0.78 MAPT (0.49) NPC1RAB9AGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed