Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389924 | 0.80 | GAA (0.42) | ADAMTS5GAAMAPTCASP1ADAMTS4 | |
| SCHEMBL10761843 | 0.79 | GAA (0.37) | GAAIDO1MAPTCASP1THRB | |
| SCHEMBL12258527 | 0.78 | HDAC8 (0.47) | ADAMTS5GAACASP1ADAMTS4CXCR4 | |
| SCHEMBL18076579 | 0.78 | TDP2 (0.43) | ADAMTS5GAACXCR4MAOAMAOB | |
| SCHEMBL7389935 | 0.71 | MAPT (0.39) | GAAMAPTALDH1A1LMNAHTT | |
| SCHEMBL7390658 | 0.71 | ADAMTS5 (0.39) | ADAMTS5GAAHDAC1 | |
| SCHEMBL1011632 | 0.71 | HDAC8 (0.57) | ADAMTS5GAAADAMTS4CXCR4MAOB | |
| SCHEMBL14357764 | 0.71 | HDAC8 (0.57) | ADAMTS5GAAADAMTS4CXCR4MAOB | |
| SCHEMBL7883790 | 0.70 | CXCR4 (0.40) | ADAMTS5GAAIDO1CASP1THRB | |
| SCHEMBL17111472 | 0.69 | NTRK1 (0.45) | ADAMTS5GAAMAPTCASP1ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541325-A | ENZYME INHIBITORS, ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-07-30 | — | — | US | disclosed |