Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943792 | 0.84 | MCHR1 (0.38) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7272654 | 0.84 | ABCB1 (0.42) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7273744 | 0.82 | HTR1A (0.38) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7276141 | 0.81 | ABCB1 (0.41) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7283846 | 0.78 | AR (0.38) | AREP300FAAH | |
| SCHEMBL7274705 | 0.78 | MCHR1 (0.37) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7275755 | 0.78 | MMP2 (0.40) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL8943454 | 0.75 | ADRA1D (0.35) | HTR1AOPRM1KDM4EHPGD | |
| SCHEMBL7278829 | 0.75 | KAT6A (0.35) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL7274188 | 0.75 | OGA (0.41) | OPRM1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |