SCHEMBL8943910

SCHEMBL8943910

CCCCOc1ccc(Nc2cccc(Oc3ccc(C(c4ccc(Oc5cccc(Nc6ccc(OCCCC)cc6)c5Nc5ccc(OCCCC)cc5)cc4)(C(F)(F)F)C(F)(F)F)cc3)c2Nc2ccc(OCCCC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CACNA1B Q00975 7/20 0.41
ADAMTS5 Q9UNA0 2/20 0.39
CACNA1H O95180 2/20 0.39
LTA4H P09960 2/20 0.38
FAAH O00519 7/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944008 0.97 FAAH (0.40) CACNA1BADAMTS5CACNA1HLTA4HFAAH
SCHEMBL8944314 0.88 ADAMTS5 (0.41) CACNA1BADAMTS5CACNA1HLTA4HFAAH
SCHEMBL8944306 0.87 LTA4H (0.50) CACNA1BADAMTS5LTA4HFAAH
SCHEMBL8943982 0.85 ALDH1A1 (0.43)
SCHEMBL8943676 0.85 LTA4H (0.42) ADAMTS5LTA4HFAAH
SCHEMBL8944276 0.84 LTA4H (0.51) ADAMTS5LTA4HFAAH
SCHEMBL8943761 0.72 ADAMTS5 (0.34) ADAMTS5LTA4H
SCHEMBL8943996 0.72 ALDH1A1 (0.47)
SCHEMBL8943655 0.71 MAPT (0.45)
SCHEMBL8943622 0.71 ALDH1A1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed