SCHEMBL8943968

SCHEMBL8943968

COc1ccc(Nc2ccc(OCc3ccc(COc4ccc(Nc5ccc(OC)cc5)cc4Nc4ccc(OC)cc4)cc3)c(Nc3ccc(OC)cc3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 8/20 0.54
KIT P10721 5/20 0.53
KDM4E B2RXH2 2/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
NPC1 O15118 1/20 0.50
THRB P10828 1/20 0.50
MAPK1 P28482 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CTSV O60911 2/20 0.47
CTSL P07711 2/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.46
EGFR P00533 2/20 0.45
ERBB2 P04626 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943590 0.90 CTSV (0.47) CSF1RKITKDM4EGAAMAPT
SCHEMBL8943581 0.86 MAPT (0.55) KDM4EGAAMAPTTDP1NPC1
SCHEMBL8944279 0.86 MAPT (0.55) KDM4EGAAMAPTTDP1NPC1
SCHEMBL8944352 0.86 EGFR (0.48) CSF1RKITGAAMAPTNPC1
SCHEMBL8944340 0.86 CTSV (0.44) CSF1RKITKDM4EGAAMAPT
SCHEMBL8944010 0.85 MAPT (0.53) KDM4EGAAMAPTTDP1NPC1
SCHEMBL8944045 0.85 CTSV (0.43) CSF1RKITGAAMAPTNPC1
SCHEMBL8944395 0.84 MAPT (0.52) KDM4EGAAMAPTTDP1NPC1
SCHEMBL8943535 0.82 MAPT (0.50) KDM4EGAAMAPTTDP1NPC1
SCHEMBL8944086 0.81 MAPT (0.49) KDM4EGAAMAPTTDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed