SCHEMBL8944352

SCHEMBL8944352

COc1ccc(Nc2ccc(OCc3ccc(COc4ccc(N(c5ccccc5)c5ccccc5)cc4)cc3)c(Nc3ccc(OC)cc3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.48
ERBB2 P04626 3/20 0.48
CTSV O60911 4/20 0.45
CTSL P07711 4/20 0.45
CSF1R P07333 2/20 0.44
ERBB4 Q15303 2/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
ALOX12 P18054 2/20 0.43
GAA P10253 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43
KIT P10721 1/20 0.43
NOX1 Q9Y5S8 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
BCHE P06276 1/20 0.42
ABCB1 P08183 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944076 0.87 MAPT (0.43) EGFRALDH1A1MAPTALOX12GAA
SCHEMBL8943968 0.86 CSF1R (0.54) EGFRERBB2CTSVCTSLCSF1R
SCHEMBL8944031 0.82 MAPT (0.45) EGFRALDH1A1MAPTALOX12GAA
SCHEMBL8943885 0.81 RAB9A (0.39) EGFRALDH1A1MAPTALOX12GAA
SCHEMBL8943663 0.80 RAB9A (0.41) EGFRALDH1A1MAPTALOX12GAA
SCHEMBL8943590 0.80 CTSV (0.47) EGFRERBB2CTSVCTSLCSF1R
SCHEMBL8943630 0.79 DRD2 (0.39) EGFRMAPTSIRT2KMT2ANPC1
SCHEMBL8943701 0.79 FGFR2 (0.44) EGFRALDH1A1MAPTALOX12GAA
SCHEMBL866939 0.77 NPC1 (0.60) EGFRERBB2ALDH1A1MAPTGAA
SCHEMBL17961922 0.77 RAB9A (0.63) EGFRALDH1A1MAPTALOX12GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed