SCHEMBL8944340

SCHEMBL8944340

COc1ccc(Nc2ccc(OCc3cccc(COc4ccc(Nc5ccc(C)cc5)cc4Nc4ccc(C)cc4)c3)c(Nc3ccc(OC)cc3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 3/20 0.44
CTSL P07711 3/20 0.44
MAOB P27338 2/20 0.44
CSF1R P07333 2/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
EGFR P00533 2/20 0.42
ERBB2 P04626 1/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
KIT P10721 1/20 0.42
MAPT P10636 2/20 0.41
KDM4E B2RXH2 2/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
GAA P10253 1/20 0.41
THRB P10828 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943590 0.95 CTSV (0.47) CTSVCTSLMAOBCSF1REGFR
SCHEMBL8943784 0.92 EGFR (0.44) CTSVCTSLEGFRERBB2MAPT
SCHEMBL8943968 0.86 CSF1R (0.54) CTSVCTSLCSF1REGFRERBB2
SCHEMBL8944086 0.84 MAPT (0.49) NCOA1NCOA3NPC1RAB9AMEN1
SCHEMBL8944343 0.84 ALDH1A1 (0.46) CTSVCTSLMAOBNCOA1NCOA3
SCHEMBL8944045 0.83 CTSV (0.43) CTSVCTSLMAOBCSF1RNPC1
SCHEMBL8943983 0.80 ALDH1A1 (0.44) NCOA1NCOA3EGFRNPC1RAB9A
SCHEMBL8944279 0.79 MAPT (0.55) EGFRNPC1RAB9AMEN1KMT2A
SCHEMBL8943581 0.79 MAPT (0.55) EGFRNPC1RAB9AMEN1KMT2A
SCHEMBL8943593 0.79 ALDH1A1 (0.47) CTSVCTSLMAOBEGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed