SCHEMBL8944110

SCHEMBL8944110

CCCCCCCCCCCCSc1ccc(N(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.46
PTGES O14684 2/20 0.45
MAPT P10636 2/20 0.45
PLK1 P53350 1/20 0.42
CYP1A2 P05177 3/20 0.41
CYP2E1 P05181 3/20 0.41
CYP3A4 P08684 3/20 0.41
CYP2C8 P10632 3/20 0.41
CYP2D6 P10635 3/20 0.41
CYP2C9 P11712 3/20 0.41
CYP2B6 P20813 3/20 0.41
CYP2C19 P33261 3/20 0.41
RYR2 Q92736 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
THRA P10827 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943972 0.94 ALDH1A1 (0.48) ALDH1A1LMNAPTGESMAPTCYP1A2
SCHEMBL8943559 0.88 RYR2 (0.47) ALDH1A1LMNAPTGESMAPTCYP1A2
SCHEMBL5315774 0.87 PTGES (0.55) ALDH1A1LMNAPTGESMAPTCYP1A2
SCHEMBL20495338 0.87 PTGES (0.55) ALDH1A1LMNAPTGESMAPTCYP1A2
SCHEMBL7260314 0.87 PTGES (0.55) ALDH1A1LMNAPTGESMAPTCYP1A2
SCHEMBL14838080 0.85 PTGES (0.52) ALDH1A1LMNAPTGESMAPTCYP1A2
SCHEMBL8943684 0.82 LTA4H (0.58) ALDH1A1LMNAMAPTCYP3A4SMN1; SMN2
SCHEMBL8944217 0.82 CA4 (0.42) ALDH1A1LMNAMEN1KMT2ANPC1
SCHEMBL5170737 0.82 ALDH1A1 (0.61) ALDH1A1LMNAMAPTRYR2MEN1
SCHEMBL8943641 0.81 LTA4H (0.58) ALDH1A1LMNAMAPTCYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed