SCHEMBL8943641

SCHEMBL8943641

CCCCOc1ccc(N(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.58
DRD2 P14416 2/20 0.54
DRD3 P35462 2/20 0.54
DRD4 P21917 1/20 0.54
L3MBTL1 Q9Y468 3/20 0.52
MAPT P10636 2/20 0.51
HPGD P15428 1/20 0.51
ATM Q13315 1/20 0.51
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
KCNH2 Q12809 2/20 0.48
AHR P35869 1/20 0.47
MLNR O43193 1/20 0.47
NR1I2 O75469 1/20 0.47
ESR1 P03372 1/20 0.47
NR3C1 P04150 1/20 0.47
PGR P06401 1/20 0.47
ADRB2 P07550 1/20 0.47
CHRM2 P08172 1/20 0.47
ADRB1 P08588 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943684 0.95 LTA4H (0.58) LTA4HDRD2DRD3DRD4L3MBTL1
SCHEMBL8943912 0.95 DRD2 (0.56) LTA4HDRD2DRD3DRD4L3MBTL1
SCHEMBL8943774 0.95 L3MBTL1 (0.57) LTA4HDRD2DRD3DRD4L3MBTL1
SCHEMBL8943988 0.93 L3MBTL1 (0.59) LTA4HDRD2DRD3DRD4L3MBTL1
SCHEMBL8943696 0.93 LTA4H (0.66) LTA4HDRD2DRD3TSHRKCNH2
SCHEMBL8944313 0.93 AHR (0.53) LTA4HDRD2DRD3DRD4L3MBTL1
SCHEMBL31258518 0.93 LTA4H (0.66) LTA4HDRD2DRD3TSHRKCNH2
SCHEMBL8943730 0.93 LTA4H (0.66) LTA4HDRD2DRD3TSHRKCNH2
SCHEMBL8943807 0.93 AHR (0.53) LTA4HDRD2DRD3DRD4L3MBTL1
SCHEMBL31258519 0.93 LTA4H (0.66) LTA4HDRD2DRD3TSHRKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed