Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CDC25C | P30307 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944331 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2KDM4EMAPK1MME | |
| SCHEMBL8944158 | 0.83 | JMJD6 (0.39) | AGTR1AGTR2TP53MAPK1 | |
| SCHEMBL6604852 | 0.81 | AGTR2 (0.36) | AGTR1AGTR2TP53MEN1KMT2A | |
| SCHEMBL8944271 | 0.81 | AGTR2 (0.36) | AGTR1AGTR2KDM4EMEN1KMT2A | |
| SCHEMBL8944450 | 0.79 | LMNA (0.39) | AGTR1AGTR2TP53KDM4E | |
| SCHEMBL8944453 | 0.79 | AGTR1 (0.46) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL6610008 | 0.74 | AGTR1 (0.39) | AGTR1AGTR2LTB4R2TP53MME | |
| SCHEMBL6611108 | 0.74 | KDM4E (0.36) | CNR2CDC25ACDC25BCDC25CKDM4E | |
| SCHEMBL17998734 | 0.70 | AGTR2 (0.57) | AGTR1AGTR2LTB4R2TP53KDM4E | |
| SCHEMBL6607829 | 0.70 | BRS3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500427-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-19 | — | — | US | disclosed |