Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 3/20 | 0.36 |
| ▸ | CCR8 | P51685 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944329 | 0.85 | CCR1 (0.40) | LMNASMN1; SMN2KDM4EGAARAB9A | |
| SCHEMBL10513245 | 0.75 | NOS2 (0.47) | LMNAKDM4EGAARAB9AHTT | |
| SCHEMBL4848307 | 0.75 | CYP1A2 (0.58) | SMN1; SMN2KDM4EGAARAB9ATP53 | |
| SCHEMBL14018680 | 0.71 | CCR1 (0.60) | LMNAKDM4EGAARAB9AHTT | |
| SCHEMBL9494309 | 0.71 | LMNA (0.43) | LMNASMN1; SMN2KDM4EGAARAB9A | |
| SCHEMBL459073 | 0.70 | KDM4E (0.61) | LMNASMN1; SMN2KDM4EGAARAB9A | |
| SCHEMBL20286668 | 0.67 | L3MBTL1 (0.49) | KDM4ERAB9ANPC1TSHRCCR1 | |
| SCHEMBL8367143 | 0.67 | KDM4E (0.49) | LMNASMN1; SMN2KDM4EGAARAB9A | |
| SCHEMBL4841795 | 0.67 | CCR1 (0.39) | SMN1; SMN2KDM4ERAB9AHTTNPC1 | |
| SCHEMBL13350372 | 0.67 | CCR1 (0.35) | NPC1CCR1CCR8CCR5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545639-A | USING 2,9-BIS(HALOMETHYL)-1,10-PHENANTHROLINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-13 | — | — | US | disclosed |