Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512211 | 0.79 | KCNH2 (0.50) | NOS2KCNH2ESR1ESR2LMNA | |
| SCHEMBL8671753 | 0.77 | CYP1A2 (0.53) | CYP1A2KDM4EGAATSHRMEN1 | |
| SCHEMBL10035363 | 0.76 | KCNH2 (0.52) | NOS2KCNH2TDP1KDM4ETP53 | |
| SCHEMBL25523587 | 0.76 | CYP1A2 (0.51) | KCNH2LMNACYP1A2KDM4EGAA | |
| SCHEMBL20855335 | 0.75 | TLR8 (0.51) | KCNH2LMNACYP1A2KDM4EGAA | |
| SCHEMBL1227402 | 0.75 | PSMB5 (0.45) | KCNH2LMNAABCB11CYP1A2CYP2D6 | |
| SCHEMBL8944472 | 0.75 | LMNA (0.42) | LMNACYP1A2TDP1KDM4ENPC1 | |
| SCHEMBL10513019 | 0.74 | KCNH2 (0.48) | NOS2KCNH2ESR1ESR2GABRP | |
| SCHEMBL20855334 | 0.72 | ALOX5 (0.39) | KCNH2HRH2HRH3 | |
| SCHEMBL1187597 | 0.71 | NOS2 (0.57) | NOS2KCNH2IKBKBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339973-A1 | Substituted 1,10-phenanthrolines | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-11-02 | — | — | EP | disclosed |