Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944585 | 0.85 | LMNA (0.42) | TSHRSIGMAR1TDP1KDM4ELMNA | |
| SCHEMBL2389512 | 0.73 | SIGMAR1 (0.47) | CA2SLC6A3HRH3TSHRHPGD | |
| SCHEMBL8459141 | 0.70 | HRH3 (0.51) | SLC6A3HRH3TSHRHPGDCXCR4 | |
| SCHEMBL303045 | 0.70 | SIGMAR1 (0.44) | SLC6A3HRH3TSHRHPGDCXCR4 | |
| SCHEMBL22651780 | 0.70 | MAOB (0.46) | NPC1KDM4EALDH1A1 | |
| SCHEMBL9690903 | 0.69 | CHRM2 (0.51) | HRH3TDP1DPP7NPC1CHRM2 | |
| SCHEMBL27571056 | 0.69 | SIGMAR1 (0.46) | SLC6A3HRH3SIGMAR1TDP1NPC1 | |
| SCHEMBL9435372 | 0.68 | ALDH1A1 (0.38) | HPGDTDP1KDM4ELMNAALDH1A1 | |
| SCHEMBL18429032 | 0.68 | CHRM2 (0.50) | HRH3CXCR4TDP1DPP7NPC1 | |
| SCHEMBL8453437 | 0.68 | HRH3 (0.42) | SLC6A3HRH3TSHRHPGDCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |