SCHEMBL8945272

SCHEMBL8945272

Cc1cc(C2CCC(C)CC2)ccc1Cc1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.38
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.32
SPHK1 Q9NYA1 1/20 0.31
SLC5A1 P13866 2/20 0.31
SLC5A2 P31639 2/20 0.31
TBK1 Q9UHD2 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945557 0.87 HTR1D (0.39) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945230 0.86 ALDH1A1 (0.33) ALDH1A1CYP3A4TSHRTDP1SPHK1
SCHEMBL8945336 0.85 ESR2 (0.37) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945075 0.84 CYP2C9 (0.44) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945103 0.83 SPHK1 (0.37) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945040 0.82 SPHK1 (0.38) ALDH1A1SPHK1
SCHEMBL7751598 0.82 ESR2 (0.52) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945152 0.81 SPHK1 (0.40) ALDH1A1CYP3A4SPHK1
SCHEMBL8945348 0.80 SPHK1 (0.41) ALDH1A1CYP3A4SPHK1
SCHEMBL8945253 0.80 SPHK1 (0.41) ALDH1A1CYP3A4SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed