SCHEMBL8945105

SCHEMBL8945105

CCCc1cccc(C2CCC(C)(Cc3ccc(N)cc3)CC2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.44
DRD3 P35462 3/20 0.44
DRD1 P21728 1/20 0.44
DRD4 P21917 1/20 0.44
DRD5 P21918 1/20 0.44
CYP19A1 P11511 1/20 0.37
CTSS P25774 3/20 0.32
CTSK P43235 3/20 0.32
DHFR P00374 1/20 0.32
PPARG P37231 1/20 0.32
ATP1A1 P05023 1/20 0.32
ATP1B1 P05026 1/20 0.32
ATP1A3 P13637 1/20 0.32
ATP1B2 P14415 1/20 0.32
ATP1A2 P50993 1/20 0.32
ATP1B3 P54709 1/20 0.32
FXYD2 P54710 1/20 0.32
ATP1A4 Q13733 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945283 0.87 DRD2 (0.44) DRD2DRD3DRD1DRD4DRD5
SCHEMBL8945440 0.87 DRD2 (0.44) DRD2DRD3DRD1DRD4DRD5
SCHEMBL8945278 0.84 HTR2C (0.46) DRD2DRD3DRD1DRD4DRD5
SCHEMBL8945344 0.82 KDM1A (0.39) DRD4MAOB
SCHEMBL8945094 0.78 SIGMAR1 (0.36) DRD2DRD3DRD1DRD4DRD5
SCHEMBL9074644 0.77 DRD2 (0.41) DRD2DRD3DRD1DRD4DRD5
SCHEMBL8945134 0.77 SIGMAR1 (0.37) DRD2DRD3DRD1DRD4DRD5
SCHEMBL8945007 0.76 DHFR (0.39) DRD2DRD3DRD1DRD4DRD5
SCHEMBL4379176 0.74 DRD3 (0.67) DRD2DRD3DRD1DRD4DRD5
SCHEMBL8945086 0.73 HTR2C (0.43) DRD2DRD3DRD1DRD4DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed