Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945400 | 0.89 | NOS3 (0.41) | EPHX2NOS3NOS1NOS2SPHK1 | |
| SCHEMBL8945000 | 0.88 | SPHK1 (0.41) | SPHK1ALDH1A1 | |
| SCHEMBL8945207 | 0.86 | CYP2C9 (0.47) | SPHK1MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL1100722 | 0.81 | ALDH1A1 (0.47) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL8945508 | 0.80 | SKP2 (0.41) | NOS3NOS1NOS2KDM4EMEN1 | |
| SCHEMBL8093485 | 0.79 | ALDH1A1 (0.43) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL31457255 | 0.78 | ALDH1A1 (0.50) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL8945154 | 0.77 | EPHX2 (0.45) | EPHX2NOS3NOS1NOS2SPHK1 | |
| SCHEMBL8945136 | 0.77 | KDM4E (0.38) | NOS3NOS1NOS2HTR1DKDM4E | |
| SCHEMBL8945167 | 0.77 | ESR2 (0.41) | SPHK1KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |