Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945176 | 0.89 | EPHX2 (0.43) | NOS3NOS1NOS2GAAMAPT | |
| SCHEMBL8945167 | 0.87 | ESR2 (0.41) | GAAMAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8945024 | 0.84 | CYP2C9 (0.51) | GAAMAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8945508 | 0.82 | SKP2 (0.41) | NOS3NOS1NOS2GAAMAPT | |
| SCHEMBL8945136 | 0.79 | KDM4E (0.38) | NOS3NOS1NOS2GAAMAPT | |
| SCHEMBL237448 | 0.79 | ALDH1A1 (0.50) | GAAMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL27497381 | 0.78 | ALDH1A1 (0.47) | GAAMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL4452070 | 0.78 | LTA4H (0.44) | GAAMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL8945000 | 0.77 | SPHK1 (0.41) | ALDH1A1SPHK1CYP3A4 | |
| SCHEMBL7751400 | 0.76 | ALDH1A1 (0.54) | NOS3NOS1NOS2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |