Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705881 | 0.80 | MMP2 (0.45) | MMP2TSHRPSMD14COPS5CHRM1 | |
| SCHEMBL30308911 | 0.80 | MMP2 (0.45) | MMP2TSHRPSMD14COPS5CHRM1 | |
| SCHEMBL11860802 | 0.77 | METAP2 (0.42) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL31353938 | 0.77 | PRMT5 (0.47) | MMP2TSHRPSMD14COPS5CHRM1 | |
| SCHEMBL8207691 | 0.77 | PRMT5 (0.47) | MMP2TSHRPSMD14COPS5KDM4E | |
| SCHEMBL31354076 | 0.73 | LMNA (0.41) | MMP2TSHRPSMD14COPS5CHRM1 | |
| SCHEMBL31354383 | 0.73 | TOP1 (0.43) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL8945454 | 0.73 | PRMT5 (0.40) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL28802010 | 0.69 | KDM4E (0.41) | TSHRCHRM1ADRA1AKDM4ELMNA | |
| SCHEMBL3237268 | 0.69 | EGFR (0.45) | MMP2TSHRCHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |