Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945159 | 0.97 | FAAH (0.35) | FAAHMGLLSCN5AABCB11CYP3A4 | |
| Hydrochloric Acid SCHEMBL8945351 | 0.83 | FAAH (0.34) | FAAHSYKLMNACYP1A2MAPK1 | |
| SCHEMBL8945300 | 0.81 | FAAH (0.37) | FAAHMGLLCYP3A4LMNACYP1A2 | |
| SCHEMBL8944906 | 0.76 | CYP1A2 (0.35) | FAAHCYP3A4LMNACYP1A2KDM4E | |
| SCHEMBL8945107 | 0.76 | FAAH (0.49) | FAAHSCN5ACYP1A2MAPK1KCNH2 | |
| SCHEMBL8945254 | 0.76 | FAAH (0.34) | FAAHLMNACYP1A2KCNH2KDM4E | |
| Hydrochloric Acid SCHEMBL8945306 | 0.76 | FAAH (0.34) | FAAHLMNACYP1A2KCNH2KDM4E | |
| SCHEMBL8945191 | 0.76 | KCNH2 (0.40) | SCN5ALMNACYP1A2KCNH2KDM4E | |
| Hydrochloric Acid SCHEMBL8945060 | 0.75 | FAAH (0.48) | FAAHSCN5ACYP1A2MAPK1KCNH2 | |
| Hydrochloric Acid SCHEMBL8945170 | 0.75 | FAAH (0.38) | FAAHLMNACYP1A2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |