SCHEMBL8945557

SCHEMBL8945557

Cc1cc(C2CCCCC2)ccc1Cc1ccc(N)cc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 2/20 0.39
BACE1 P56817 2/20 0.38
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NOS3 P29474 2/20 0.35
NOS1 P29475 2/20 0.35
NOS2 P35228 2/20 0.35
SLC18A3 Q16572 1/20 0.35
NUDT1 P36639 1/20 0.35
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945272 0.87 ESR2 (0.38) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945230 0.85 ALDH1A1 (0.33) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945085 0.84 HTR1D (0.39) HTR1DBACE1ALDH1A1CYP3A4TSHR
SCHEMBL8945214 0.83 HTR1D (0.42) HTR1DBACE1ALDH1A1CYP3A4TSHR
SCHEMBL8945075 0.83 CYP2C9 (0.44) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945154 0.82 EPHX2 (0.45) HTR1DBACE1ALDH1A1CYP3A4TSHR
SCHEMBL8945040 0.81 SPHK1 (0.38) ALDH1A1
SCHEMBL8945152 0.80 SPHK1 (0.40) ALDH1A1CYP3A4
SCHEMBL7751400 0.80 ALDH1A1 (0.54) BACE1ALDH1A1CYP3A4TSHRTDP1
SCHEMBL9445287 0.80 ACMSD (0.43) BACE1NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed