Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8945738 | 0.98 | HTT (0.30) | HTTPDE5APDE6CPDE11A | |
| SCHEMBL8946140 | 0.91 | HTT (0.32) | HTTPDE5APDE6CPDE11A | |
| Hydrochloric Acid SCHEMBL8945828 | 0.89 | HTT (0.31) | HTTPDE5APDE6CPDE11A | |
| SCHEMBL8945930 | 0.83 | HTT (0.34) | HTTPDE5ACTSD | |
| SCHEMBL8945770 | 0.81 | SLC6A2 (0.36) | HTT | |
| Hydrochloric Acid SCHEMBL8945896 | 0.81 | HTT (0.33) | HTTPDE5A | |
| Hydrochloric Acid SCHEMBL8945853 | 0.81 | SLC6A2 (0.36) | HTT | |
| SCHEMBL8945967 | 0.79 | HRH4 (0.34) | HTTPDE5A | |
| SCHEMBL8945973 | 0.79 | MEN1 (0.36) | HTTPDE5A | |
| SCHEMBL8946006 | 0.79 | HTT (0.32) | HTTPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | claimed |
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | disclosed |