Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8945964 | 0.99 | HTT (0.32) | HTTPDE5AKDM4EHSD17B10 | |
| SCHEMBL8945930 | 0.85 | HTT (0.34) | HTTPDE5AKDM4EHSD17B10GAA | |
| Hydrochloric Acid SCHEMBL8945896 | 0.83 | HTT (0.33) | HTTPDE5AKDM4EHSD17B10GAA | |
| SCHEMBL8945973 | 0.81 | MEN1 (0.36) | HTTPDE5AKDM4EHSD17B10GAA | |
| SCHEMBL8946140 | 0.81 | HTT (0.32) | HTTPDE5AKDM4EHSD17B10GAA | |
| SCHEMBL8945967 | 0.81 | HRH4 (0.34) | HTTPDE5AKDM4EHSD17B10GAA | |
| SCHEMBL8946091 | 0.81 | SLC6A2 (0.38) | HTTKDM4EHSD17B10GAAHPGD | |
| Hydrochloric Acid SCHEMBL8945756 | 0.80 | HRH4 (0.34) | HTTPDE5AKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL8945737 | 0.80 | SLC6A2 (0.37) | HTTKDM4EHSD17B10GAAHPGD | |
| SCHEMBL8945957 | 0.79 | HTT (0.31) | HTTPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | claimed |