Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946005 | 0.71 | ALOX5 (0.32) | NPC1RAB9AALDH1A1 | |
| SCHEMBL9425099 | 0.71 | ALOX5 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8945763 | 0.70 | CXCR1 (0.32) | — | |
| SCHEMBL10587312 | 0.69 | AOC3 (0.42) | ALDH1A1LMNA | |
| SCHEMBL7748143 | 0.66 | MAPK10 (0.65) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL8945904 | 0.65 | ALDH1A1 (0.32) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL255251 | 0.65 | GAA (0.76) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL8506869 | 0.64 | NPC1 (0.66) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL8507006 | 0.64 | NPC1 (0.66) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL27386734 | 0.64 | NPC1 (0.61) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |