Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946066 | 0.85 | ALOX5 (0.33) | ALOX5KMT2A | |
| SCHEMBL8945985 | 0.85 | RECQL (0.36) | ALOX5KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL8945840 | 0.85 | ALOX5 (0.35) | ALOX5KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL8946039 | 0.83 | CXCR1 (0.32) | ALOX5KMT2A | |
| SCHEMBL8945946 | 0.83 | KDM4E (0.38) | KMT2AMEN1 | |
| SCHEMBL9425099 | 0.82 | ALOX5 (0.33) | ALOX5KMT2A | |
| Hydrochloric Acid SCHEMBL8945763 | 0.81 | CXCR1 (0.32) | KMT2A | |
| SCHEMBL9425592 | 0.74 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL8945969 | 0.71 | OPRM1 (0.44) | NPC1ALDH1A1RAB9A | |
| SCHEMBL8945876 | 0.69 | ALOX5 (0.35) | ALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | claimed |
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | disclosed |