Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8945945 | 0.97 | NPEPPS (0.38) | NPEPPSDRD2ALDH1A1MAPTHRH4 | |
| SCHEMBL8946052 | 0.83 | ALDH1A1 (0.40) | NPEPPSDRD2ALDH1A1MAPTCXCR4 | |
| Water SCHEMBL8945872 | 0.82 | ALDH1A1 (0.39) | NPEPPSDRD2ALDH1A1MAPTCXCR4 | |
| Water SCHEMBL8945879 | 0.82 | ALDH1A1 (0.39) | NPEPPSDRD2ALDH1A1MAPTCXCR4 | |
| SCHEMBL8946051 | 0.81 | NPEPPS (0.37) | NPEPPSDRD2ALDH1A1MAPTCXCR4 | |
| Hydrochloric Acid SCHEMBL8946103 | 0.79 | NPEPPS (0.36) | NPEPPSDRD2ALDH1A1MAPTCXCR4 | |
| Hydrochloric Acid SCHEMBL8945986 | 0.79 | NPEPPS (0.36) | NPEPPSDRD2ALDH1A1MAPTCXCR4 | |
| SCHEMBL8945923 | 0.75 | HRH4 (0.35) | DRD2HRH4 | |
| SCHEMBL8945967 | 0.74 | HRH4 (0.34) | DRD2ALDH1A1MAPTHRH4 | |
| Hydrochloric Acid SCHEMBL8945921 | 0.74 | HRH4 (0.34) | DRD2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | claimed |