Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946223 | 0.85 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9ABCHE | |
| SCHEMBL8946048 | 0.84 | BCHE (0.44) | MEN1KMT2ANPC1RAB9ABCHE | |
| SCHEMBL7621050 | 0.76 | BCHE (0.51) | MEN1KMT2ANPC1RAB9ABCHE | |
| Hydrochloric Acid SCHEMBL8544417 | 0.76 | BCHE (0.51) | MEN1KMT2ANPC1RAB9ABCHE | |
| SCHEMBL8946193 | 0.74 | BCHE (0.46) | MEN1KMT2ABCHESRD5A2ROCK1 | |
| SCHEMBL7620277 | 0.73 | BCHE (0.71) | MEN1KMT2ANPC1RAB9ABCHE | |
| SCHEMBL8946189 | 0.73 | ROCK1 (0.43) | MEN1KMT2ANPC1RAB9ASRD5A2 | |
| SCHEMBL8946215 | 0.69 | SLC6A2 (0.56) | BCHESLC6A2ROCK1 | |
| SCHEMBL9674458 | 0.67 | ROCK1 (0.46) | MEN1KMT2ANPC1RAB9ASRD5A2 | |
| SCHEMBL8946156 | 0.67 | SLC6A2 (0.49) | MEN1KMT2ABCHESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509400-B1 | 1-(Pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles, intermediates and a process for their preparation, and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-07-03 | — | — | EP | disclosed |
| US-5519131-A | CYCLIZATION OF HYDROXYALKYLAMINO COMPOUND IN THE PRESENCE OF STRONG BASE SUCH AS SODIUM HYDRIDE OR POTASSIUM TERT-BUTOXIDE | HOECHST MARION ROUSSEL INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5276156-A | Antidepressants, treatment of Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-01-04 | — | — | US | disclosed |
| US-5214038-A | Cholinesterase inhibitors, antidepressants, cognition activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0509400-A1 | 1-(Pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles, intermediates and a process for their preparation, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-10-21 | — | — | EP | disclosed |