Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CRHBP | P24387 | 2/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946845 | 0.86 | LMNA (0.70) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL6016478 | 0.85 | MEN1 (0.69) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL1969326 | 0.83 | DHODH (0.51) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL8946570 | 0.83 | CRHBP (0.62) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL31324952 | 0.82 | MEN1 (0.58) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL13274916 | 0.81 | KMT2A (0.57) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL10376718 | 0.80 | TDP1 (0.50) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL10377250 | 0.79 | CYP1A2 (0.56) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL11552012 | 0.79 | DHODH (0.49) | MEN1KMT2AHPGDMAPTGAA | |
| SCHEMBL8946509 | 0.79 | L3MBTL1 (0.60) | MEN1KMT2AHPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |