Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RORB | Q92753 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782995 | 0.85 | LDHA (0.47) | DHODHMEN1GAAHPGDKMT2A | |
| SCHEMBL8946347 | 0.79 | MEN1 (0.64) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL1969326 | 0.76 | DHODH (0.51) | DHODHMEN1GAAMAPTHPGD | |
| SCHEMBL1970118 | 0.75 | KMO (0.50) | DHODHMEN1GAAMAPTHPGD | |
| SCHEMBL18573216 | 0.75 | CNR1 (0.42) | DHODHMEN1MAPTKMT2ALDHA | |
| SCHEMBL10783212 | 0.75 | KMT2A (0.50) | DHODHMEN1MAPTHPGDKMT2A | |
| SCHEMBL12501075 | 0.74 | CYP1A2 (0.68) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL269867 | 0.73 | HNF4A (0.53) | RORBKMODCLRE1BALDH1A1KDM4E | |
| SCHEMBL30546841 | 0.73 | PTGER1 (0.46) | DHODHKMT2A | |
| SCHEMBL10778477 | 0.72 | DHODH (0.50) | DHODHMEN1MAPTKMT2AMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005231-A2 | Isoquinoline derivatives, process for their preparation and pharmaceutical preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-14 | — | — | EP | disclosed |