Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946926 | 0.87 | NTRK1 (0.53) | S1PR4NTRK1CRHBPCRHR2 | |
| SCHEMBL8946542 | 0.85 | ANPEP (0.40) | S1PR4NTRK1ANPEPCNR1PTGER3 | |
| SCHEMBL8946569 | 0.85 | LPAR1 (0.46) | MAPK14NTRK1LMNA | |
| SCHEMBL8946576 | 0.84 | L3MBTL1 (0.51) | NTRK1LMNAANPEPCNR1 | |
| SCHEMBL8946580 | 0.84 | NPC1 (0.41) | S1PR4NTRK1LMNAANPEPCNR1 | |
| SCHEMBL8946713 | 0.82 | L3MBTL1 (0.41) | S1PR4NTRK1CNR1 | |
| SCHEMBL8946528 | 0.81 | LMNA (0.41) | S1PR4LMNAANPEPCNR1 | |
| SCHEMBL8946727 | 0.81 | LMNA (0.43) | S1PR4LMNACNR1 | |
| SCHEMBL8946840 | 0.80 | TP53 (0.42) | S1PR4 | |
| SCHEMBL8946520 | 0.79 | PIK3R1 (0.43) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |