Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 13/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946567 | 0.87 | NTRK1 (0.45) | NTRK1POLBMAPK1KDM4EMEN1 | |
| SCHEMBL8946460 | 0.86 | NTRK1 (0.43) | NTRK1KMT2A | |
| SCHEMBL8946441 | 0.86 | NTRK1 (0.48) | NTRK1MAPK1MEN1KMT2A | |
| SCHEMBL8946563 | 0.86 | NTRK1 (0.57) | NTRK1MAPK1MEN1KMT2A | |
| SCHEMBL8946576 | 0.85 | L3MBTL1 (0.51) | NTRK1MAPK1KMT2A | |
| SCHEMBL8946671 | 0.83 | NTRK1 (0.48) | NTRK1MAPK1MEN1KMT2A | |
| SCHEMBL8946624 | 0.83 | NTRK1 (0.43) | NTRK1MAPK1TP53DPP4KDM4E | |
| SCHEMBL8946682 | 0.81 | NTRK1 (0.45) | NTRK1MAPK1TP53MEN1KMT2A | |
| SCHEMBL8946363 | 0.80 | NTRK1 (0.51) | NTRK1POLBMAPK1MEN1KMT2A | |
| SCHEMBL8946547 | 0.80 | L3MBTL1 (0.49) | NTRK1POLBMAPK1TP53DDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |