Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946654 | 0.85 | L3MBTL1 (0.55) | L3MBTL1NTRK1KDM4EMEN1KMT2A | |
| SCHEMBL8946857 | 0.82 | L3MBTL1 (0.53) | L3MBTL1NTRK1KDM4EMEN1KMT2A | |
| SCHEMBL8946920 | 0.82 | L3MBTL1 (0.50) | L3MBTL1NTRK1MEN1KMT2A | |
| SCHEMBL8946858 | 0.81 | ADORA3 (0.53) | L3MBTL1NTRK1GRIK1KDM4EMEN1 | |
| SCHEMBL8946589 | 0.81 | L3MBTL1 (0.49) | L3MBTL1NTRK1MEN1KMT2A | |
| SCHEMBL8946576 | 0.80 | L3MBTL1 (0.51) | L3MBTL1NTRK1KMT2AALDH1A1TSHR | |
| SCHEMBL8946540 | 0.80 | SMN1; SMN2 (0.49) | L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL8946750 | 0.80 | L3MBTL1 (0.48) | L3MBTL1NTRK1MEN1KMT2A | |
| SCHEMBL8946507 | 0.80 | NTRK1 (0.44) | NTRK1KDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL8946617 | 0.80 | L3MBTL1 (0.53) | L3MBTL1NTRK1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |