Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844752 | 1.00 | HTR2A (0.34) | HTR2AHTR2CHTR2BALDH1A1MAOA | |
| SCHEMBL9844750 | 1.00 | HTR2A (0.34) | HTR2AHTR2CHTR2BALDH1A1MAOA | |
| SCHEMBL8946539 | 0.82 | HTR2A (0.36) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8946537 | 0.82 | HTR2A (0.36) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8946545 | 0.82 | HTR2A (0.36) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8946673 | 0.81 | HTR2A (0.40) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8946679 | 0.81 | HTR2A (0.40) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8946672 | 0.81 | HTR2A (0.40) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8946661 | 0.73 | MAOA (0.32) | HTR2AHTR2CHTR2BALDH1A1MAOA | |
| SCHEMBL8946653 | 0.73 | MAOA (0.32) | HTR2AHTR2CHTR2BALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |